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近年來,科學界熱烈討論益生菌和益生元跟舒緩濕疹的關係。基於益生菌和益生元的天然特性,長期服用並不會引起像類固醇般的嚴重副作用。因此,如果證實它們真的具有舒緩濕疹的作用,這將會濕疹治療的一大突破。

的確,近年的有不少研究燃起這個希望。例如,於二零一零年發表的研究結果指出,服用某品種的益生菌加益生元可以明顯改善學前兒童臨床濕疹症狀中某些指標。不過,二零一四年亦有研究報告表示益生菌對濕疹並沒有額外的治療效果。這顯示爭論仍舊持續。

相反來說,益生菌作為預防濕疹手段就較為科學界肯定。二零一四年剛發表了一項綜合研究,當中結集了二十七份研究結果,分析了二千七百九十七人的數據,發現懷孕其間和嬰兒時期服用益生菌補充品的確與統計學上的濕疹風險明顯下跌有關。當然,將來更詳細的研究還是需要的。







In the past decades, scientists have been heavily discussing the association between probiotics/prebiotics and relief or prevention of eczema. Based on the natural properties of probiotics/prebiotics, long-term usage of them do not result in severe side effects like those caused by steroids. Therefore, if they are proven to possess eczema-relieving property, it will be a huge breakthrough in eczema treatment.

Indeed, there have been a number of research studies lighting up this hope. For example, a research results published in 2010 revealed that taking certain kinds of probiotics and prebiotics can significantly improve some parameters of clinical eczema symptoms in preschool children. But a study just published in 2014 indicated probiotics does not bear extra beneficial effect to the treatment. This shows controversy still persists.

On the contrary, taking probiotics as a preventive measure is more generally accepted by scientists. A meta-analysis published in 2014 included 27 different research papers and analyzed 2797 people’s data, discovering that probiotics supplementation during pregnancy and early infancy was indeed related to statistically significant reduction in risk of eczema. Surely, further investigation is still needed.

Gerasimov et al. Probiotic Supplement Reduces Atopic Dermatitis in Preschool Children: A Randomized, Double-blind, Placebo-controlled, Clinical Trial. Am J Clin Dermatol. 2010;11(5):351-61. Yang et al. Efficacy of Probiotic Therapy on Atopic Dermatitis in Children: A Randomized, Double-blind, Placebo-controlled Trial. Allergy Asthma Immunol Res. 2014 May;6(3):208-15. Mansfield et al. Comparative Probiotic Strain Efficacy in the Prevention of Eczema in Infants and Children: A Systematic Review and Meta-analysis. Mil Med. 2014 Jun;179(6):580-92.





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